The Need
Current bone fixation devices are typically made from stainless steel or titanium, which are significantly stiffer than bone and often require surgical removal. Magnesium alloys offer a promising alternative due to their bone-like mechanical properties and bioresorbability. However, commercial magnesium alloys degrade too quickly and suffer from poor mechanical performance and biocompatibility due to brittle intermetallic phases. There is a critical need for bioresorbable materials with optimized mechanical strength, corrosion resistance, and biocompatibility.

The Technology
Researchers at The Ohio State University have developed a patented thermomechanical processing method for magnesium alloys that enhances mechanical properties while maintaining biocompatibility and corrosion resistance. The process involves strategic alloying (including Mn for grain refinement) and a multi-stage heat treatment guided by CALPHAD modeling to dissolve brittle intermetallics and prevent their reformation. This enables improved workability (rolling, extrusion, or forging) and strength without compromising the alloy’s bioresorbable nature.

Commercial Applications
• Temporary bone fixation devices
• Load-bearing orthopedic implants
• Bone scaffolding materials
• Surgical hardware for trauma and reconstructive procedures

Benefits/Advantages
• Tunable degradation rate aligned with bone healing timelines
• Enhanced mechanical strength (yield stress up to 300 MPa) and ductility (up to 33%)
• Rare-earth-free composition improves biocompatibility and regulatory acceptance
• Reduced need for secondary surgeries due to natural resorption
• Scalable manufacturing process compatible with existing metal forming techniques